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DISSECTION P2381 - ESOC25-1554 OPTIMIZING PATIENT SELECTION FOR FIRST-LINE RITUXIMAB THERAPY IN PRIMARY ANGIITIS OF THE CENTRAL NERVOUS SYSTEM Jaroslava Paulasova Schwabova 1 , Katerina Benesova 1 , Tereza Ruzickova 1 , Silvia Kmetonyova 1 , Martin Elisak 1 , Ivana Sarbochova 1 , Hana Magerova 1 , Anna Olserova 1 , Jansky Petr 1 , Ales Tomek 1 1 1Department of Neurology, Charles University, Second Faculty of Medicine and Motol University Hospital, Prague, Czech Republic Background and Aims: Primary angiitis of the central nervous system (PACNS) is a rare yet serious condition, often challenging to diagnose and treat